Listar por autor "Espinosa, Nelson"
Mostrando ítems 1-15 de 15
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Antagonist muscle co-activation during straight walking and its relation to kinematics: Insight from young, elderly and Parkinson's disease
Arias, Pablo; Espinosa, Nelson; Robles-García, Verónica; Cao, Ricardo; Cudeiro, Javier (Elsevier, 2012-03-21)[Abstract] Increased antagonist muscle co-activation of the lower limb during walking seems to be an adaptive process to the physiological changes of aging, in order to gain joint stability. In the healthy subjects this ... -
Balancing the excitability of M1 circuitry during movement observation without overt replication
Arias, Pablo; Robles-García, Verónica; Corral Bergantiños, Yoanna; Espinosa, Nelson; Mordillo-Mateos, Laura; Grieve, Kenneth; Oliviero, Antonio; Cudeiro, Javier (Frontiers, 2014-09-17)[Abstract] Although observation of a movement increases the excitability of the motor system of the observer, it does not induce a motor replica. What is the mechanism for replica suppression? We performed a series of ... -
Bootstrap testing for cross-correlation under low firing activity
González Montoro, Aldana María; Cao, Ricardo; Espinosa, Nelson; Cudeiro, Javier; Mariño Alfonso, Xurxo (Springer, 2015-04-14)[Abstract] A new cross-correlation synchrony index for neural activity is proposed. The index is based on the integration of the kernel estimation of the cross-correlation function. It is used to test for the dynamic ... -
Central fatigue induced by short-lasting finger tapping and isometric tasks: a study of silent periods evoked at spinal and supraspinal levels
Arias, Pablo; Robles-García, Verónica; Corral Bergantiños, Yoanna; Madrid, Andy; Espinosa, Nelson; Valls-Solé, Josep; Grieve, Kenneth; Oliviero, Antonio; Cudeiro, Javier (Elsevier, 2015-08-01)[Abstract] The neural substrates of fatigue induced by muscular activity have been addressed in depth in relation to isometric tasks. For these activities, when fatigue develops, it has been noted that the duration of the ... -
Changes in Visual Responses in the Feline dLGN: Selective Thalamic Suppression Induced by Transcranial Magnetic Stimulation of V1
Labra, Carmen de; Rivadulla, Casto; Grieve, Kenneth; Mariño Alfonso, Xurxo; Espinosa, Nelson; Cudeiro, Javier (Oxford University Press, 2006-08-14)[Abstract] Transcranial magnetic stimulation (TMS) of the cortex can modify activity noninvasively and produce either excitatory or inhibitory effects, depending on stimulus parameters. Here we demonstrate controlled ... -
Cortical Modulation of the Transient Visual Response at Thalamic Level: A TMS Study
Espinosa, Nelson; Mariño Alfonso, Xurxo; Labra, Carmen de; Cudeiro, Javier (PLoS ONE, 2011-02-10)[Abstract] The transient visual response of feline dorsal lateral geniculate nucleus (dLGN) cells was studied under control conditions and during the application of repetitive transcranial magnetic stimulation at 1 Hz ... -
Cross nearest-spike interval based method to measure synchrony dynamics
González Montoro, Aldana María; Cao, Ricardo; Faes, Christel; Molenberghs, Geert; Espinosa, Nelson; Cudeiro, Javier; Mariño Alfonso, Xurxo (American Institute of Mathematical Sciences, 2014-02)[Abstract] A new synchrony index for neural activity is de ned in this paper. The method is able to measure synchrony dynamics in low ring rate scenarios. It is based on the computation of the time intervals between ... -
Different sources of nitric oxide mediate neurovascular coupling in the lateral geniculate nucleus of the cat
Labra, Carmen de; Rivadulla, Casto; Espinosa, Nelson; Dasilva, Miguel; Cao, Ricardo; Cudeiro, Javier (Frontiers, 2009-09-08)[Abstract] Understanding the link between neuronal responses (NRs) and metabolic signals is fundamental to our knowledge of brain function and it is a milestone in our efforts to interpret data from modern non invasive ... -
Effects of movement imitation training in Parkinson's disease: a virtual reality pilot study
Robles-García, Verónica; Corral Bergantiños, Yoanna; Espinosa, Nelson; García-Sancho, Carlos; Sanmartín, Gabriel; Flores, Julián; Cudeiro, Javier; Arias, Pablo (Elsevier, 2016-05)[Abstract] Background. Hypometria is a clinical motor sign in Parkinson's disease. Its origin likely emerges from basal ganglia dysfunction, leading to an impaired control of inhibitory intracortical motor circuits. Some ... -
Effects on EEG of low (1Hz) and high (15Hz) frequency repetitive transcranial magnetic stimulation of the visual cortex: a study in the anesthetized cat
Espinosa, Nelson; Labra, Carmen de; Rivadulla, Casto; Mariño Alfonso, Xurxo; Grieve, Kenneth; Cudeiro, Javier (Bentham Open, 2007-12-07)[Abstract] Here we confirm our earlier findings that showed 1Hz rTMS over the primary visual cortex of the anesthetized cat, known to cause inhibition of the cortex, induces an increase in power in the slow, delta band of ... -
Functional two-way analysis of variance and bootstrap methods for neural synchrony analysis
González Montoro, Aldana María; Cao, Ricardo; Espinosa, Nelson; Cudeiro, Javier; Mariño Alfonso, Xurxo (BioMed Central, 2014-08-12)[Abstract] Background: Pairwise association between neurons is a key feature in understanding neural coding. Statistical neuroscience provides tools to estimate and assess these associations. In the mammalian brain, ... -
Motor facilitation during real-time movement imitation in Parkinson’s disease: a virtual reality study
Robles-García, Verónica; Arias, Pablo; Sanmartín, Gabriel; Espinosa, Nelson; Flores, Julián; Grieve, Kenneth; Cudeiro, Javier (Elsevier, 2013-08-06)[Abstract] Background: Impaired temporal stability and poor motor unit recruitment are key impairments in Parkinsonian motor control during a whole spectrum of rhythmic movements, from simple finger tapping to gait. Therapies ... -
Spatiotemporal gait patterns during overt and covert evaluation in patients with Parkinson’s disease and healthy subjects: is there a hawthorne effect?
Robles-García, Verónica; Corral Bergantiños, Yoanna; Espinosa, Nelson; Jácome, M. A.; García-Sancho, Carlos; Cudeiro, Javier (Human Kinetics, 2015)[Abstract] Parkinson's disease (PD) and aging lead to gait impairments. Some of the disturbances of gait are focused on step length, cadence, and temporal variability of gait cycle. Under experimental conditions gait can ... -
The effects of expectancy on corticospinal excitability: passively preparing to observe a movement
Arias, Pablo; Robles-García, Verónica; Espinosa, Nelson; Corral Bergantiños, Yoanna; Mordillo-Mateos, Laura; Grieve, Kenneth; Oliviero, Antonio; Cudeiro, Javier (American Physiological Society, 2014-01-08)[Abstract] The corticospinal tract excitability is modulated when preparing movements. Earlier to movement execution, the excitability of the spinal cord increases waiting for supraspinal commands to release the movement. ... -
Validity of the finger tapping test in Parkinson’s disease, elderly and young healthy subjects: is there a role for central fatigue?
Arias, Pablo; Robles-García, Verónica; Espinosa, Nelson; Corral Bergantiños, Yoanna; Cudeiro, Javier (Elsevier, 2012-05-03)[Abstract] Objective: The main goal of this work is to evaluate the validity of the finger tapping test (FT) to detect alterations in rhythm formation. Methods: We use FT to study the alterations in motor rhythm in three ...